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Metagenome Program
The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … experimental approaches to assess microbial activity across ecosystems.  By studying microbial communities and …
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Viral Genomics Group
… group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of viral infections. The … ISME J.   15 , 1569–1584 Roux, S. et al. (2019) Cryptic inoviruses revealed as pervasive in bacteria and archaea …
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Plant Program
… user projects, the JGI’s Plant Program delves into the natural world’s potential to address global … to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … evolution. It also utilizes advanced tools, including deep learning algorithms for gene annotation and protein folding …
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Data Ecosystem
To expand access to integrated data, improve tools and infrastructure as well … cohesive data standards, the JGI partners with a number of facilities.  … Through its partnership with NERSC and the … to facilitate these efforts. Particular areas of emphasis will be the development of tools and …
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Natural Prodcast Episode 11: Marnix Medema
… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural … things. But before that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- … . So this is an algorithm that identifies, using machine learning models, that very tiny precursor peptide, encoding …
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Simon Roux
Dr. Roux joined the JGI in 2017 to lead viral genomics research as part of the Metagenome … 11, 237 Roux et al., 2023. iPHoP: An integrated machine learning framework to maximize host prediction for … biotechnology 39, 578-585. Roux et al., 2019. Cryptic inoviruses revealed as pervasive in bacteria and archaea …
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Learning to Look
Machine learning approach significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” readers need to look for a number of distinguishing features. Several …
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Natural Prodcast Episode 9: Roger Linington
… episode 9 of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British … for Ray Andersen there, and had a very enjoyable time learning about natural products science. DAN:  Yeah, great. … hand, in order to build a machine learning model that would look at all of the data that’s in PubMed, and pick out …
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Metabolomics Program
The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … demystify the complexity of dissolved organic matter (DOM) across a variety of environments. ENVnet allows us to …
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Microbial Program
… cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … datasets, particularly for uncultivated microorganisms, by sequencing large populations of bacteria and archaea in …
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Natural Prodcast Episode 14: Nigel Mouncey
… 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from here I can get … lying around at home. And I would just pick them up and look at the pictures for a while. And then I was able to … we’ve done a lot on our spinosyns. We had a huge amount of learnings to apply to this second product, the UK2A base …
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Fungal & Algal Program
The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, environmental … is a five-year project to sequence 1000 fungal genomes from across the Fungal Tree of Life, from an international …
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