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… of Energy Office of Science user facility supported by the Biological and Environmental Research program, the Joint … earth, and environmental systems for energy and infrastructure security. The BER research program seeks to … being compatible with our existing fuel distribution infrastructure. Sequencing, DNA synthesis, and metabolomics …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … of dissolved organic matter (DOM) across a variety of environments. ENVnet allows us to uncover globally distributed molecules with conserved structures, offering fresh insights into DOM's composition. …

So, I’ve always known Roger as an expert in natural product structure elucidation, but more recently, he’s been leading … Atlas , or NPAtlas, a freely accessible natural products structure database, which is going to be just invaluable to … the future of the natural products field as it relates to structure elucidation and genome mining, and how we might …

… understanding of the role small molecules play in diverse biological systems, sheds light on nutrient cycling, and … Platform delivers rich metabolite profiles from diverse biological and environmental samples using advanced liquid … media in which they grow, as well as different types of environments (e.g. soil, lake).  A wide range of metabolites …

… let’s see what caves have to offer because they’re unique environments. These are structures that are millions of years old. This is — rooms … Yeah. DAN UDWARY: So it’s medicinal chemistry but with biological systems? BRIAN BACHMANN: That’s right. And it’s …

… a class of natural product with a really cool chemical structure. We try to explain it, but it’s chemistry, so I … there. So, check out the show notes, and I’ll put up some structures and link to some resources you can use to get … So that’s the fundamental aspects. And the second, from a biological potential application perspective, is because …

… to have a job that really got me back to more fundamental biological discovery. And I virtually just kind of stumbled … we’ve just been cataloging who’s there in these different environments. And now it’s really about what are they doing. … whole set of bioassays here at JGI. We don’t have the infrastructure. It’s too many resources for us. So we need good …

… to find novel functions that may impact microbiome structure and biogeochemical cycles. Research Team    … A …

So he could see really into this– so he could look into the structure, really seeing that. And I’m always just looking … trees, and then trying to see if the trees make sense, biologically. So if I can see patterns in that certain … which is still hard to do. We are mining a lot of environments to see where are environments that have the …

… biogeochemistry — questions of relevance to DOE’s Office of Biological and Environmental Research (BER) missions .  …