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I kind of lost count of how many times Brad used the words “fun” and “magical” when describing his science, which is … because I was always swimming or surfing. And you know, 25 hours a day we’re at the beach practically. It was just – … has been a lot of fun for us in recent years. Started in 2015, when two things happened. One, a new graduate student …

FENICAL: I had begun diving when I was a teenager, about 15. I grew up in Northern California. And we’d go down to … And that ultimately– not in the ’40s, but really in the ’50s– led to a little more common use of scuba. And very … I think you’re right. I mean, that too was an issue. What function, what utility, what kind of applications might …

… references to the news, that’s why. But it was a really fun conversation. And I think you’ll enjoy it. So here it … so we worked on the Salinospora genomes. That was a really fun project. We had Brad on and he kind of waxed poetic … a marine actinomycete bacterium. So they look kind of like fungi but also make these mycelia. They kind of look like …

DAN UDWARY: Yeah, for sure. CASSANDRA QUAVE: Yeah, and it’s funny. It’s kind of weird to me that people are actually … than HIV/AIDS does every year in the US and it has since 2005 even though we technically have a number of different … to distill. But in the Chemical Reviews paper, we found 459 isolated compounds. Now the weaknesses in a lot of those …

… of natural products biosynthesis. I think it will be fun to be able to provide a semi-regular forum for postdocs … We know each other pretty well. So I feel like it’s always fun to talk to you. I’m particularly interested… Well, … over time. And yeah, I mean, that was let’s see, maybe 5,6,7 years ago, and I’ve – I haven’t looked back. ALISON: …

… where I was a graduate student. Aflatoxin, of course, is a fungal natural product which is a liver toxin when humans accidentally eat it, but it has a really fun and interesting biosynthetic pathway, and I’ll have to … is, everyone in the field has come together in an unusually friendly and cohesive way, and defined, the pieces that go …

Uncovering associations between plant roots and fungi that can help or harm plant host health. The Science … of Science of the U.S. DOE under Contract No. DE-AC02-05CH11231 within the framework of CSP 1974 “1KFG: … a European Research Council starting grant (MICRORULES 758003), the ‘Priority Programme: Deconstruction and …

… way to explore biosynthetic chemistry. It’s some fun topics, and I think you’ll enjoy it! So, that’s this … I went to group meeting and came back and it was just so fun looking at this as someone who had a bit more of a … of molecules can be thought of as signals or have other functions depending on their concentration and their …

… efforts in paired-omics data sets and seeking to interpret function from BGCs. It’s a long, wide ranging conversation … that you do, then it’s very easy to think that, OK, I find 25 gene clusters, there must be 25 new compounds. Or everything that has similarity to a gene …

… at the company. So I was the first chemist. So after having fun analyzing gene clusters for several months, they said, … just did a low-resolution shotgun pass where we sequenced 500 runs. And then we used those to find gene clusters in … be difficult to write a grant on right now like another P450 or glycosyltransferase. You probably would have a hard …

Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a functional role. We started from that. Evolution doesn’t … it’s been selected for. So if you think about the possible functions that each one metabolite could have, then you …

… actually listen to this. JACLYN WINTER: I think that’d be fun. Yeah. Let’s do it. What if we just start like swearing, … And you have these different types of particulate like 2.5, 10 PPMs and just the size of the particle and how far … Yeah. It reminds me almost working with Bill back in the ’50s and ’60s of the golden age of antibiotic discoveries. …