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With collaborative user projects, the JGI’s Plant Program … A major focus are biofuel feedstock species and plant-microbe interactions, advancing efforts to create renewable …

… week is Professor Cassandra Quave from Emory University, with joint appointments in the School of Medicine and … curator there, with a broad range of experimental work on plants for drug discovery in antibiotics, anticancer, and … a really interesting field that I guess– so I’m more of a microbe guy, and as is Alison, or not a guy, but [LAUGHS] a …

… the world who have made additions to antiSMASH, contributed features. That has been great fun to actually work with so … called “disease suppression”, where the microbiome of a plant, so the bacteria living on and inside the roots are … a nice example of going from a whole community with many microbes, hundreds of gene clusters, and then being able to …

… that I wanted to include it. This is a conversation with Marc Chevrette. Marc is a postdoc in Jo Handelsman’s … was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods was these damn … As a host, and a little bit of my newer work is focused on plants, but in both cases, you know, these molecules are how …

The Plant Program Advisory Committee is chartered to offer … on the effective management and strategic objectives of the plant program. The committee serves as the program's key …

… and we talk about an ongoing project I’ve been working with him on as an exploration into the secondary metabolism … local marine environment. I went out and picked up marine plants, I picked up animals. And I asked the simple … you think about the fact that, when plants and animals and microbes evolve, they evolve to make molecules that improve …

Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As much as we … to do an independent study on ethnobotany of some of the plants that people were using for medicines in this very … this the needle in the Haystack. Because if we have 10,000 features which one do we look at because we are a small lab? …

… techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with microeukaryotes, enhances our understanding of … sequencing technologies to explore microbial diversity — with an emphasis on bacteria and archaea, and including …

… we’re going to be presenting some conversations we had with scientists in the field of natural products. So, it’s a … ag[riculture] and I really liked – I became interested in plant disease in part because of what happened in my Peace … use natural products necessarily. Fungi are large. They’re microbes, but they’re large microbes. And they have all …

And so we also sequence a lot of fungi, and we sequence plants. And so we started thinking about if we had a … now. The website is fully accessible, and most of the features that we expect are in there. The only thing missing … of Utah , about her secondary metabolism research on novel microbes and bioactive compounds in the Great Salt Lake. …

At the end of the day, all the content produced by microbes the result of millions of years of evolution. And if we could actually link terms to those emerging features that are natural to this complex, then we might … could be a reasonable number if you are talking about a plant and a microbe interacting very stably. So it makes …

… in making this happen. We had a really fun conversation with Roger about all this, in terms of how to build an … transcriptomics, metabolomics, and natural products in plants, fungi, and microorganisms. If you want to … see you next time!  … Episode Transcript …   … This episode features our conversation with Roger Linington , from Simon …