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…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which are not essential for … by their native hosts. We are developing cell-free based systems to express BGCs that alleviate the constraints of …

The SMAC is chartered by the Secondary Metabolites Program Head and report back to them. The …

With collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to … development of complex biomolecules — which can include antimicrobial and anti-pest compounds.  The program is working … biology to ecosystem processes through model laboratory ecosystems. They are small plastic growth chambers where plants …

… on to talk about JGI’s vision for secondary metabolism, his past in industry in developing natural products for … I did my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for … with a contract manufacturer to actually have them build a plant for production and fermentation and transfer that …

… works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With advanced mass …

… to do an independent study on ethnobotany of some of the plants that people were using for medicines in this very … tell us about this squid-microbe relationship. Or is it a microbial community with microbial community relationship?  … so my collaborator and I have this idea that they work like pastry bags almost and so they are essentially squeezed out …

… to meet the ever-changing demands of our users. … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic … The SMC provides complete sequence and annotation data for secondary metabolite biosynthetic gene clusters (BGCs) …

… of the role small molecules play in diverse biological systems, sheds light on nutrient cycling, and leads to the … At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of experimental … samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types …

DAN: Well, it is and it isn’t. It depends on different systems of secondary metabolism and the things that are in … for a long time by many, many bacteria – and fungi and plants. And so that’s the power and the promise of, I guess, … they think the field needs and what they’ve done in the past and maybe what JGI can do to help drive secondary …

… about natural products and the science and scientists of secondary metabolism. Natural products, secondary metabolites, and specialized metabolites all refer to the … to medicine, the environment, and human health. As the JGI acts on its goals in — and builds out its capabilities …

The JGI’s Microbial Program focuses on using cutting-edge … provides high-quality, large-scale genomic data to advance microbial research that drives sustainable solutions in … … Integrated Microbial Genomes — Virus Resources … Genomes Online Database … Microbial Program in Detail … Projects and …

… the special, natural chemical compounds that you find in plants, fungi and bacteria, basically all living things. … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … products that would cause some, you know, major historical events and craziness in human history.  ALISON: Yeah, that …