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…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which are not essential for … metabolites produced by bacteria, fungi, algae and plants. These compounds are key to organisms' interactions …

… The SMAC is chartered by the Secondary Metabolites Program Head and report back to them. The …

… on to talk about JGI’s vision for secondary metabolism, his past in industry in developing natural products for … I did my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for … with a contract manufacturer to actually have them build a plant for production and fermentation and transfer that …

… curator there, with a broad range of experimental work on plants for drug discovery in antibiotics, anticancer, and … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in … can find all of that information on virtual and in-person events again on my website. You can also– I’d also encourage …

… With collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying soils, … humanity. A major focus are biofuel feedstock species and plant-microbe interactions, advancing efforts to create …

… about natural products and the science and scientists of secondary metabolism. Hey everybody, this is Dan with … for a long time about the evolution and natural products systems. This conversation came about because he challenged … could be a reasonable number if you are talking about a plant and a microbe interacting very stably. So it makes …

… works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With advanced mass … to gain insights into how small molecules function within plants, microbes, and ecosystems. Identifying and analyzing …

… genomes and their predicted hosts (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of new genes with … variants and new CRISPR-Cas types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive …  Nat Microbiol. 3(9):1023-1031 Harrington LB et al. (2017) A thermostable Cas9 with increased lifetime in human …

… target is based on 98% of the total available hours.   FY 2017 DOE Metrics 1,598 unique* JGI users in FY2017 … Q1 – Report on new computational developments for improving microbial, metagenomic, or plant genome assemblies. [Download PDF] Q2 – Report on …

… Plants are complex organisms that harbor a fantastic … including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …

… in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated … Woyke T ., Doud D. F. R., Schulz F. The trajectory of microbial single-cell sequencing. Nat Methods 14(11): 1045-1054 (2017). Schulz F., Yutin N., Ivanova N. N., Ortega D. R., Lee …

… of the role small molecules play in diverse biological systems, sheds light on nutrient cycling, and leads to the … At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of experimental … samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types …