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Metabolomics Program
Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … scientists are able to link metabolic activity with gene expression, providing deeper insights into functional …
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Plant Program
… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global … to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … Centers. The  Plant Gene Atlas initiative develops gene expression catalogs across JGI Plant Flagship …
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Secondary Metabolites Program
… growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … pathway analysis, optimization of cell- and cell free-based expression platforms, tools and data for deciphering …
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DNA Synthesis Program
Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … the development of biofuels, biochemicals and other bioenergy solutions.  The program has been a pioneering …
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Plant-Microbial Interactions Group
… single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … strains, whereby they can modulate host metabolism, gene expression and phenotype. We have recently identified … importance. … We are using cutting-edge single-cell profiling methods, including single-cell RNA-seq, …
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Special Initiatives & Programs
Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for … and 200 polar/500 nonpolar metabolomics samples, and should generally conform to the guidelines for our  CSP Large Scale … and synthesis on behalf of the U.S. Department of Energy Bioenergy Research Centers.  The Centers are intended to …
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Fungal & Algal Program
… diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the … on large-scale sequencing efforts that survey the vast phylogenetic and ecological diversity of fungi and algae, …
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Metabolomics Technology Group
Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical datasets to improve our …
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Mission
… by the Biological and Environmental Research program, the Joint Genome Institute provides advanced genomic capabilities, … and microbes) relevant to the DOE science mission areas of bioenergy and environmental microbiome processes.  Among the … are at the core of many environmental processes, and the genetic makeup of microbial species and communities forms …
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Natural Prodcast Episode 11: Marnix Medema
… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … was a proposal on synthetic biology of engineering gene expression in bacteria – however, the professor was actually …
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Natural Prodcast Episode 20: Brian Bachmann
… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … if you want– if you really want to, you can do heterologous expression. You can do homologous expression techniques and …
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Products
… percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in … alignment files 384/454 Fungal Transcriptome RNA for expression profiling and genome annotation (single organism). Note: …
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