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… through end-to-end automation — and further advancing sequence applications, single cell genomics, biodesign, and … [QA/QC]), large-scale liquid handling automation, and sequence analysis. … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … and expand the Tree of Life. We then investigate the coding potential to find novel functions that may impact microbiome … complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… bioprospecting vs biopiracy, early stage drug discovery in general, and a possible data-driven future for plant natural … culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … and not necessarily in medicines. [CHUCKLES] Selfishly, what can or should we be doing to help the plant …

… When submitting sequences to the JGI DNA Synthesis program, please include … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an … written by M. Wayne Davis or commercial options include SnapGene . …

… focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … that are from candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The “Great … is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …

… the JGI’s Plant Program delves into the natural world’s potential to address global challenges by exploring plants’ … to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … plant growth and productivity. These insights have the potential to inform strategies that improve agricultural …

… energy and ecosystem management. The program aims to generate high-quality genomic datasets, particularly for … single cell approaches. This includes linking strain-level genetic variation to ecological niche adaptations.  Single … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from …

… as part of the International Biodiversity Drug Discovery consortium doing natural products isolation/structure … and to go through all of these abstracts and titles and to fish out data about new molecules that have been found. And … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, cloned into vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs …

… the vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, and … This research helps translate their genomic potential into practical applications, including sustainable … energy solutions. Algae, too, offer a wealth of untapped potential, with their ability to capture carbon and produce …

… metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … JGI scientists are able to link metabolic activity with gene expression, providing deeper insights into functional … a web-based service returns a list of scored reaction and gene matches associated with metabolites and a list of …

… diversity within secondary metabolites, expanding their potential applications in the bioeconomy including biofuels, … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … uncover these hidden biochemical resources by exploring the genetic pathways responsible for their synthesis. The …