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    Screencap of green algae video for PNAS paper
    Green Algae Reveal One mRNA Encodes Many Proteins
    A team of researchers has found numerous examples of polycistronic expression – in which two or more genes are encoded on a single molecule of mRNA – in two species of green algae.

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    Advances in Rapidly Engineering Non-model Bacteria
    CRAGE is a technique for chassis (or strain)-independent recombinase-assisted genome engineering, allowing scientists to conduct genome-wide screens and explore biosynthetic pathways. Now, CRAGE is being applied to other synthetic biology problems.

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    Maize can produce a cocktail of antibiotics with a handful of enzymes. (Sam Fentress, CC BY-SA 2.0)
    How Maize Makes An Antibiotic Cocktail
    Zealexins are produced in every corn variety and protect maize by fending off fungal and microbial infections using surprisingly few enzymes.

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    Poplar (Populus trichocarpa and P. deltoides) grow in the Advanced Plant Phenotyping Laboratory (APPL) at Oak Ridge National Laboratory in Tennessee. Poplar is an important biofuel feedstock, and Populus trichocarpa is the first tree species to have its genome sequenced — a feat accomplished by JGI. (Image courtesy of Oak Ridge National Laboratory, U.S. Dept. of Energy)
    Podcast: Xiaohan Yang on A Plantiful Future
    Building off plant genomics collaborations between the JGI and Oak Ridge National Laboratory, Xiaohan Yang envisions customizing plants for the benefit of human society.

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    Expansin complex with cell wall in background. (Courtesy of Daniel Cosgrove)
    Synthesizing Microbial Expansins with Unusual Activities
    Expansin proteins from diverse microbes have potential uses in deconstructing lignocellulosic biomass for conversion to renewable biofuels, nanocellulosic fibers, and commodity biochemicals.

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    High oleic pennycress. (Courtesy of Ratan Chopra)
    Pennycress – A Solution for Global Food Security, Renewable Energy and Ecosystem Benefits
    Pennycress (Thlaspi arvense) is under development as a winter annual oilseed bioenergy crop. It could produce up to 3 billion gallons of seed oil annually while reducing soil erosion and fertilizer runoff.

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    Artistic interpretation of CheckV assessing virus genome sequences from environmental samples. (Rendered by Zosia Rostomian​, Berkeley Lab)
    An Automated Tool for Assessing Virus Data Quality
    CheckV can be broadly utilized by the research community to gauge virus data quality and will help researchers to follow best practices and guidelines for providing the minimum amount of information for an uncultivated virus genome.

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    Unicellular algae in the Chlorella genus, magnified 1300x. (Andrei Savitsky)
    A One-Stop Shop for Analyzing Algal Genomes
    The PhycoCosm data portal is an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, compare them, and visualize supporting experimental data.

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    Artistic interpretation of how microbial genome sequences from the GEM catalog can help fill in gaps of knowledge about the microbes that play key roles in the Earth's microbiomes. (Rendered by Zosia Rostomian​, Berkeley Lab)
    Podcast: A Primer on Genome Mining
    In Natural Prodcast: the basics of genome mining, and how JGI researchers conducted it in IMG/ABC on thousands of metagenome-derived genomes for a Nature Biotechnology paper.

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    Image of Octopus Springs for the CSP annual call
    Letters of Intent are due April 12, 2021 for the annual Community Science Program (CSP) call focused on large-scale genomic science projects that address specific areas of special emphasis and exploit the diversity of JGI capabilities.

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    SIP engagement webinar
    “SIP technologies at EMSL and JGI” Webinar
    The concerted stable isotope-related tools and resources of the JGI and the Environmental Molecular Sciences Laboratory (EMSL) may be requested by applying for the annual “Facilities Integrating Collaborations for User Science” (FICUS) call.

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    CSP Functional Genomics Call Ongoing
    The CSP Functional Genomics call helps users translate genomic information into biological function. Proposals submitted by July 31, 2021 will be part of the next review.

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    Aerial photo of the switchgrass diversity panel late in the 2020 season at the Kellogg Biological Station in Michigan. (Robert Goodwin)
    A Team Effort Toward Targeted Crop Improvements
    A multi-institutional team has produced a high-quality reference sequence of the complex switchgrass genome. Building off this work, researchers at three DOE Bioenergy Research Centers have expanded the network of common gardens and are exploring improvements to switchgrass.

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    Artistic interpretation of how microbial genome sequences from the GEM catalog can help fill in gaps of knowledge about the microbes that play key roles in the Earth's microbiomes. (Rendered by Zosia Rostomian​, Berkeley Lab)
    Uncovering Novel Genomes from Earth’s Microbiomes
    A public repository of 52,515 microbial draft genomes generated from environmental samples around the world, expanding the known diversity of bacteria and archaea by 44%, is now available .

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    Green millet (Setaria viridis) plant collected in the wild. (Courtesy of the Kellogg lab)
    Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
    In Nature Biotechnology, a very high quality reference Setaria viridis genome was sequenced, and for the first time in wild populations, a gene related to seed dispersal was identified.

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News & Publications
Home › News Releases
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January 19, 2017

Seeking Structure With Metagenome Sequences

From sample to structure. Top: Researchers gathering samples from Great Boiling Spring in Nevada. Left: a snapshot of aligned metagenomic sequences. Each row is a different sequence (the different colors are the different amino acid groups). Each position (or column) is compared to all other positions to detect patterns of co-evolution. Bottom: the strength of the top co-evolving residues is shown as blue dots, these are also shown as colored lines on the structure above. The goal is to make a structure that makes as many of these contacts as possible. Right: a cartoon of the protein structure predicted. The protein domain shown is from Pfam DUF3794, this domain is part of a Spore coat assembly protein SafA. (Image of Great Boiling Spring by Brian Hedlund, UNLV. Protein structure and composite image by Sergey Ovchinnikov, UW)Metagenomics database helps fill in 10 percent of previously unknown protein structures For proteins, appearance matters. These important molecules largely form a cell’s structures and carry out its functions: proteins control growth and influence mobility, serve as catalysts, and transport or store other molecules. Comprised of long amino acid chains, the one-dimensional amino acid sequence… [Read More]

January 16, 2017

Tracking Antarctic Adaptations in Diatoms

Scanning electron micrograph of two cells of Fragilariopsis cylindrus. Shown are two silica shells (Frustules) in valve view. Magnification: 15,000X; scale bar: 5 μm (Image credit: Gerhard S. Dieckmann)Comparative genome analysis provides clues on how climate change might impact evolutionary adaptation limits Diatoms are a common type of photosynthetic microorganism, found in many environments from marine to soil; in the oceans, they are responsible for more than a third of the global ocean carbon captured during photosynthesis. This leads to a significant amount… [Read More]

January 10, 2017

Industrial Biotechnology Leader to Assume the Helm of the DOE Joint Genome Institute

Nigel MounceyAfter a 9-month national search, Nigel Mouncey, currently Research and Development Director for Bioengineering and Bioprocessing at Dow AgroSciences LLC, has been selected as the Director of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility. “Nigel brings the perfect set of scientific and management skills as… [Read More]

November 17, 2016

Engineering a More Efficient System for Harnessing Carbon Dioxide

A MPI video featuring study senior author Tobias Erb discussing this project may be viewed at http://bit.ly/ErbCETCH.Despite the vast diversity of organisms on the planet that express enzymes for the conversion of carbon dioxide into such organic compounds as sugars – as plants do through photosynthesis – the efforts to harness these capabilities to transform CO2 into high-value products such as biofuel and renewable chemicals have met with limited success. While… [Read More]

November 2, 2016

2017 DOE Joint Genome Institute Community Science Program Allocations Announced

John Cushman of the University of Nevada seeks to establish the common or crystalline ice plant (Mesembryanthemum crystallinum L.) as a DOE JGI Flagship Genome species. (Image by Krzysztof Ziarnek, Kenraiz CC BY-SA 4.0 Wikipedia)Portfolio additions build upon contributions in sustainable biofuels, plant microbiomes and biogeochemistry. From deep within the Earth to the upper atmosphere, the organisms and ecosystems highlighted in the 37 projects selected for the 2017 Community Science Program (CSP) of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User… [Read More]

September 7, 2016

How Fungi Help Trees Tolerate Drought

The crosscut shows the fungal tissues - the fungal mantle around the root tip and the the fungal network of tendrils that penetrates the root of plants, or Hartig Net, between Pinus sylvestris plant root cells - in green. (Image by Maira de Freitas Pereira, INRA Nancy.)Genome of world’s most common fungal symbiont sheds light on drought resistance role The mutualistic relationship between tree roots and ectomycorrhizal (ECM) fungi has been shaping forest ecosystems since their inception. ECM fungi are key players supporting the growth, health and stress tolerance of forest trees globally, such as oak, pine, spruce, birch and beech,… [Read More]

September 6, 2016

10 New Projects to be Supported Under Joint DOE User Facility Initiative

This diagram from Petr Baldrian’s proposal shows the seasonal differences in the carbon cycle processes in the temperate and boreal coniferous forests. During vegetation seasons, depicted by September on the left, photosynthesis products are allocated to soil via tree roots. When photosynthesis stops in winter, depicted by March on the right, decomposition is the most important carbon cycle process. (Image courtesy of Petr Baldrian)The U.S. Department of Energy Joint Genome Institute (DOE JGI) and the Environmental Molecular Sciences Laboratory (EMSL) have accepted 10 projects submitted during the 2017 call for proposals for their joint “Facilities Integrating Collaborations for User Science” (FICUS) initiative. These new research projects all involve collaboration between two user facilities that are stewarded by the DOE Office… [Read More]

August 17, 2016

Unveiled: Earth’s Viral Diversity

virome-graphic_art-by-Z-Rostomian-LBNLEnvironmental datasets help researchers double the number of microbial phyla known to be infected by viruses. The number of microbes in, on, and around the planet – on the order of a nonillion, or 1030 – is estimated to outnumber the stars in the Milky Way. Microbes are known to play crucial roles in regulating… [Read More]

August 15, 2016

Expanding the Stable of Workhorse Yeasts

One of the genomes sequenced for this study was of the yeast Scheffersomyces stipitis. (Courtesy of Tom Jeffries, University of Wisconsin-Madison)New genome sequences target next generation of yeasts with improved biotech uses The yeast Saccharomyces cerevisiae was a part of human civilization before history was recorded. It is essential for making bread, beer and wine, and it is ubiquitous. It is not, however, typical of the more than 1,500 yeast species found around the world…. [Read More]

July 19, 2016

Comparing Fungal Secretions to Uncover Carbon Compound Degradation Pathways

Pyrenochaeta sp. DS3sAY3a growing in liquid culture. As the fungus grows, brown-colored manganese oxides are formed. Here, the oxides can be seen associated with biomass and suspended in solution. (Carolyn Zeiner)Their unassuming appearances may cause them to be overshadowed by the plants or animals in their natural habitats, but fungi play key roles in maintaining their ecosystems. From breaking down leaf litter and decaying wood in forests to cleaning contaminated soils and waters, fungal enzymes are being characterized for potential use in a wide variety… [Read More]
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