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    Data yielded from RIViT-seq increased the number of sigma factor-gene pairs confirmed in Streptomyces coelicolor from 209 to 399. Here, grey arrows denote previously known regulation and red arrows are regulation identified by RIViT-seq; orange nodes mark sigma factors while gray nodes mark other genes. (Otani, H., Mouncey, N.J. Nat Commun 13, 3502 (2022). https://doi.org/10.1038/s41467-022-31191-w)
    Streamlining Regulon Identification in Bacteria
    Regulons are a group of genes that can be turned on or off by the same regulatory protein. RIViT-seq technology could speed up associating transcription factors with their target genes.

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    (PXFuel)
    Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
    In a special issue of the journal Synthetic Biology, JGI scientific users share how they’ve worked with the JGI DNA Synthesis Science Program and what they’ve discovered through their collaborations.

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    A genetic element that generates targeted mutations, called diversity-generating retroelements (DGRs), are found in viruses, as well as bacteria and archaea. Most DGRs found in viruses appear to be in their tail fibers. These tail fibers – signified in the cartoon by the blue virus’ downward pointing ‘arms’— allow the virus to attach to one cell type (red), but not the other (purple). DGRs mutate these ‘arms,’ giving the virus opportunities to switch to different prey, like the purple cell. (Courtesy of Blair Paul)
    A Natural Mechanism Can Turbocharge Viral Evolution
    A team has discovered that diversity generating retroelements (DGRs) are not only widespread, but also surprisingly active. In viruses, DGRs appear to generate diversity quickly, allowing these viruses to target new microbial prey.

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    Photograph of a stream of diatoms beneath Arctic sea ice.
    Polar Phytoplankton Need Zinc to Cope with the Cold
    As part of a long-term collaboration with the JGI Algal Program, researchers studying function and activity of phytoplankton genes in polar waters have found that these algae rely on dissolved zinc to photosynthesize.

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    This data image shows the monthly average sea surface temperature for May 2015. Between 2013 and 2016, a large mass of unusually warm ocean water--nicknamed the blob--dominated the North Pacific, indicated here by red, pink, and yellow colors signifying temperatures as much as three degrees Celsius (five degrees Fahrenheit) higher than average. Data are from the NASA Multi-scale Ultra-high Resolution Sea Surface Temperature (MUR SST) Analysis product. (Courtesy NASA Physical Oceanography Distributed Active Archive Center)
    When “The Blob” Made It Hotter Under the Water
    Researchers tracked the impact of a large-scale heatwave event in the ocean known as “The Blob” as part of an approved proposal through the Community Science Program.

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    A plantation of poplar trees. (David Gilbert)
    Genome Insider podcast: THE Bioenergy Tree
    The US Department of Energy’s favorite tree is poplar. In this episode, hear from ORNL scientists who have uncovered remarkable genetic secrets that bring us closer to making poplar an economical and sustainable source of energy and materials.

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    HPCwire Editor's Choice Award (logo crop) for Best Use of HPC in the Life Sciences
    JGI Part of Berkeley Lab Team Awarded Best Use of HPC in Life Sciences
    The HPCwire Editors Choice Award for Best Use of HPC in Life Sciences went to the Berkeley Lab team comprised of JGI and ExaBiome Project team, supported by the DOE Exascale Computing Project for MetaHipMer, an end-to-end genome assembler that supports “an unprecedented assembly of environmental microbiomes.”

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    With a common set of "baseline metadata," JGI users can more easily access public data sets. (Steve Wilson)
    A User-Centered Approach to Accessing JGI Data
    Reflecting a structural shift in data access, the JGI Data Portal offers a way for users to more easily access public data sets through a common set of metadata.

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    Phytozome portal collage
    A More Intuitive Phytozome Interface
    Phytozome v13 now hosts upwards of 250 plant genomes and provides users with the genome browsers, gene pages, search, BLAST and BioMart data warehouse interfaces they have come to rely on, with a more intuitive interface.

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    screencap from Amundson and Wilkins subsurface microbiome video
    Digging into Microbial Ecosystems Deep Underground
    JGI users and microbiome researchers at Colorado State University have many questions about the microbial communities deep underground, including the role viral infection may play in other natural ecosystems.

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    Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical output due to growth and viability constraints. Cell extracts provide an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By separating the production of enzymes (during growth) and the biochemical production process (in cell-free reactions), this framework enables biosynthesis of diverse chemical products at volumetric productivities greater than the source strains. (Blake Rasor)
    Boosting Small Molecule Production in Super “Soup”
    Researchers supported through the Emerging Technologies Opportunity Program describe a two-pronged approach that starts with engineered yeast cells but then moves out of the cell structure into a cell-free system.

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    These bright green spots are fluorescently labelled bacteria from soil collected from the surface of plant roots. For reference, the scale bar at bottom right is 10 micrometers long. (Rhona Stuart)
    A Powerful Technique to Study Microbes, Now Easier
    In JGI's Genome Insider podcast: LLNL biologist Jennifer Pett-Ridge collaborated with JGI scientists through the Emerging Technologies Opportunity Program to semi-automate experiments that measure microbial activity in soil.

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    A view of the mangroves from which the giant bacteria were sampled in Guadeloupe. (Hugo Bret)
    Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
    Harnessing JGI and Berkeley Lab resources, researchers characterized a giant - 5,000 times bigger than most bacteria - filamentous bacterium discovered in the Caribbean mangroves.

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    In their approved proposal, Frederick Colwell of Oregon State University and colleagues are interested in the microbial communities that live on Alaska’s glacially dominated Copper River Delta. They’re looking at how the microbes in these high latitude wetlands, such as the Copper River Delta wetland pond shown here, cycle carbon. (Courtesy of Rick Colwell)
    Monitoring Inter-Organism Interactions Within Ecosystems
    Many of the proposals approved through JGI's annual Community Science Program call focus on harnessing genomics to developing sustainable resources for biofuels and bioproducts.

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    Coloring the water, the algae Phaeocystis blooms off the side of the sampling vessel, Polarstern, in the temperate region of the North Atlantic. (Katrin Schmidt)
    Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
    As warm-adapted microbes edge polewards, they’d oust resident tiny algae. It's a trend that threatens to destabilize the delicate marine food web and change the oceans as we know them.

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News & Publications
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April 22, 2014

Every Day is Earth Day @JGI

Earth Day at JGIMore than four decades ago, the first celebration of Earth Day raised the idea of protecting the environment to a greater public awareness. Today, the annual event is a reminder of the longstanding goal to provide a cleaner, healthier and sustainable environment for everyone to live in. Here at the U.S. Department of Energy Joint… [Read More]

April 10, 2014

The Genomics of Energy & Environment – in Poetry

In honor of National Poetry Month, we’re celebrating an underutilized method of communicating our science: poetry. According to Merriam-Webster, poetry is defined as, “writing that formulates a concentrated imaginative awareness of experience in language chosen and arranged to create a specific emotional response through meaning, sound, and rhythm.” As proof that science can (and has)… [Read More]

March 20, 2014

Great Prairie soil study in Biomass magazine

“During the study, MSU researchers sought to compare the microbial populations of different soils sampled from sites that were once native prairie with 100 years of agricultural cultivation. The experiment yielded nearly 400 billion letters of code, which amounts to more than 130 human genome equivalents.” Learn more about the complexities of soil and then… [Read More]

October 29, 2013

Get the latest edition of JGI Newsletter, The Primer

Get the latest edition of JGI Newsletter, The Primer [Read More]

September 18, 2013

Microbial dark matter study in Wired

“The idea was to go after underrepresented branches of microbial diversity – so-called Microbial Dark Matter – for which additional information would have a disproportionately large effect on the tree’s overall shape. In pursuit of these recluses, Rinke and his colleagues sampled nine different habitats that were likely to house exotic or otherwise overlooked organisms:… [Read More]

September 15, 2013

Yellowstone Hot Springs: A Hotbed of Microbial Life

Niki Parenteau (left) and Beverly Pierson (right) sample red-layer phototrophic mats at Fairy Geyser, August 2007 (Image courtesy of Bill Inskeep)[Note: This article originally appeared in the Autumn 2013 issue of the JGI Primer.] Life on Earth finds a way to survive almost anywhere there is a source of energy to support it. In Yellowstone National Park (YNP), this phenomenon is in the extreme by microorganisms that thrive in harsh, acidic hot springs found unsuitable… [Read More]

August 28, 2013

Microbial dark matter study in Treehugger

“Space comes to mind as the last frontier for finding new forms of life, but we still have not explored all of the planet on which we are living. Biologists venture to places both extreme and mundane in the quest to learn more about Earth. Courtesy of the DOE Joint Genome Institute, here is a photo… [Read More]

July 27, 2013

Advancing soybean science on Iowa Public Radio

““It’s amazing to see the explosion that’s gone on in the plant world,” said Jeremy Schmutz, a plant genomicist at the U.S. Department of Energy Joint Genome Institute in California and the HudsonAlpha Institute for Biotechnology in Alabama. In 2010, his team completed the soybean genome sequence, which is a roadmap that shows every piece of soybean DNA.”… [Read More]

July 26, 2013

Microbial “who done it?” in R&D magazine

“One of the keys to commercialization of advanced biofuels is the development of cost-competitive ways to extract fermentable sugars from lignocellulosic biomass. The use of enzymes from thermophiles—microbes that thrive at extremely high temperatures and alkaline conditions—holds promise for achieving this. Finding the most effective of these microbial enzymes, however, has been a challenge. That… [Read More]

July 22, 2013

Leaf-cutter ants project in Milwaukee Journal Sentinel

“These bacteria and these fungi have evolved for millions of years to deconstruct plant biomass,” said Frank Aylward, a graduate student at the University of Wisconsin-Madison who studies leaf-cutter ants and their fungus gardens. “We should try to learn from them and find out how it occurs in nature.” Read more at JSOnline.com about this… [Read More]
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