Published in:
Stand Genomic Sci 5(2) , 248-53 (Nov 30 2011)
Author(s):
DOI:
10.4056/sigs.2075298
Abstract:
ClaMS – “Classifier for Metagenomic Sequences” – is a Java application for binning assembled contigs in metagenomes using user-specified training sets and initial parameters. Since ClaMS trains on sequence composition-based genomic signatures, it is much faster than binning tools that rely on alignments to homologs; ClaMS can bin ~20,000 sequences in 3 minutes on a laptop with a 2.4 GHx Intel Core 2 Duo processor and 2 GB RAM. ClaMS is meant to be a desktop application for biologists and can be run on any machine under any Operating System on which the Java Runtime Environment can be installed.