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… through end-to-end automation — and further advancing sequence applications, single cell genomics, biodesign, and … [QA/QC]), large-scale liquid handling automation, and sequence analysis. … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated …

… When submitting sequences to the JGI DNA Synthesis program, please include … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … We have another drug that’s in development here, not yet professionally transmitted to the pharmaceutical … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger … certain taxa come up that might be there, but not as abundant. So as the community changes and also the secondary …

… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … to explore microbial diversity — with an emphasis on bacteria and archaea, and including those associated with … microorganisms, by sequencing large populations of bacteria and archaea in their natural environments using …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … potential but I don’t think we know how to harness it yet.  I don’t think – it’s actually one of the things that I … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … open source project and can be downloaded here , or, better yet, installed as an Anaconda package .)  And so that does …

… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … JACKIE: Very nice. DAN: And then just to make this abundantly clear to our audience, so the goal here then is …

… chemical compounds that you find in plants, fungi and bacteria, basically all living things. When your crazy Aunt … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … it seemed like we didn’t know very much about that world yet. So I am very interested to hear more about it. And I’m …

… Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the … limitations. That’s what you’ve got in front of you. And yet it is more data than you can understand, right? So you …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … It is truly a secondary product of evolution that, yet, does not fulfill in a specialized role or even an … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … prioritizing, OK, which gene clusters are more highly abundant in the suppressive soils compared to the conducive …