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… computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties encoded within those genomes. Our aim is to more fully capture microbial and … on the assembly of metagenomic sequence data into microbial genomes, which is of fundamental value to improving our …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with … Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though not … development and adoption of classroom modules Currently 206 genomes have been selected with 11 published manuscripts …

… apply to each facility with separate review schedules and selection processes, making it difficult to propose projects …

… Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … catalog of viral, microbial, and microeukaryote genomes and mobile genetic elements, linked to custom … environments. Integrating metatranscriptomes and metagenomes can, for instance, deepens our understanding of …

… I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … so many bacteria, because it is so easy to sequence their genomes comparatively to especially plants. So yeah, so from … then, that we try to find biosynthetic gene clusters in genomes is by homology search. We’re building on the backs …

… and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … culture collections to produce hundreds of diverse algal genomes, which will be made accessible through the PhycoCosm … for microbial eukaryotes, build fungal and algal pangenomes, and integrate multi-omics tools to enhance …

… led a team that  identified a protein , PtrbHLH011, within poplar involved in plant growth, lignin production, and … The Impact With increased lignin and iron, engineered poplar can be used to develop bioproducts for industrial … such as cement or adhesives. Described as the “DOE Tree,” poplar is considered one of the  Flagship Plants for …

… Plant Flagship Genomes are selected through discussion with the JGI Plant … Advisory Committee and DOE, designating a set of JGI plant genomes that are the most important to DOE mission and plant … datasets to further gene function research. The  Open Green Genomes (OGG) project seeks to develop comparative high …

… While an ever-increasing number of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these viruses … filter, cluster, annotate, and bin viruses from metagenomes. mSystems 9:e00888-24. …

… is acting very strongly. There is very strong purifying selection, and what matters is a final product. So it … Whereas the nature of the evolutionary force, the selection there is shaping the pathway itself on the … it is more related to what JGI does, which is sequence genomes. And we just published last year in the Nature …

… and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … a number of years earlier as one of the first Streptomyces genomes that had just not  been released yet. And there was … genes and domains, to identify enzyme coding genes that are signatures for the presence of a specific type of …

… profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …