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… mechanisms that enable fungi and algae to play a vital role in carbon cycling, biodegradation and biogeochemistry. This … of fungi and algae. These organisms play a critical role in ecological processes such as carbon cycling, biodegradation and biogeochemistry. The …

… compounds, Alison. They are – if you can imagine – two carbons in a triple bond attached to two carbons in a double bond attached to two carbons in a triple bond. And then you know, the rest of a … from their core chemical structure: one “ene” – that’s two carbons attached by a double bond – and to “ynes” – two more …

… potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying soils, interacting with other organisms, … our understanding of plants’ biological and ecological roles to foster sustainable solutions for energy, … energy into chemical energy — and its implications for carbon sequestration, renewable energy and agricultural …

… or fungal metabolism by microbes, will have a functional role. We started from that. Evolution doesn’t invent stuff … For example, lipids– doesn’t matter if it has one extra carbon or two or one less, at the end of the day, it’s … of evolution that, yet, does not fulfill in a specialized role or even an integrated metabolic role– I’ll come back …

… it was worth putting that time into. ALISON:  What was the role of potential collaborators? Like, what did you pitch to … in order to start to make predictions about environmental roles of these compounds? Can we perform studies such as … and Class C? And if so, do they pay play some complimentary role in the environment? So you can imagine using the data …

… As a large-scale data generator, the JGI has a key role to play in providing high-quality, structured and …

… and natural product molecules obviously play a huge role in ecology through cell-cell communication, chemical … and work within the DOE emission space of bioenergy, carbon cycling, biogeochemistry, bioproducts. So we cannot … We really focus on terrestrial ecosystems, but we work in coastal environments, brackish environments, et cetera. Now …

… about. He works with methylotrophs, which are a group of carbon-fixing bacteria that I would say are are still fairly … in Seattle . And she studies bacteria that grow on one-carbon compounds like methanol and methane. And I really … back up through the sediment it’ll get to this Goldilocks zone where there’s some oxygen available that has diffused …

… ALISON: Like such a large diversity can have similar effects, I think is also really interesting. Because … But… DAN: Yeah, there are a lot of ways to put together carbon molecules. Chemistry is pretty limitless. All right, … a brief history of drug discovery and natural products’ role in it. All right, this is probably one of the most …

… them. They’re filter feeders that have a really important role on the reef and other environments. And you can find … and what a couple of other groups were doing played a big role because we started finding common elements, DAN:  But …

… plants. And so I think of nature as giving us the gift of blueprints to interesting natural products that we can use … And we looked at both the chemistry and the pharmacological effects against bacteria.  And what was interesting is that … DNA synthesis, metabolomics. Where do you see the role of a big place like JGI in terms of helping out your …

… don’t know a lot about them by their mate, what their role in nature, how have they been selected for or how do … for what I wanted to do. Also studying evolution and the role of the secondary metabolites– ALISON TAKEMURA: And this …