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… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … assembly, analysis, annotation, verification, creation of genome browsers, etc. The users, collaborators, and JGI … of data produced at the facility, provided this is done in a timely fashion. The publications resulting from …

… in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the … belong to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A …

… for a while. Moving forward, I’m hoping to get a new one out every two weeks. This time, we’ve got a great … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … this collection in total contains approximately 100,000 bacterial strains, and a hundred thousand fungal strains. …

… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … The Integrated Microbial Genomes & Microbiomes system ( IMG/M ) supports the …

… and expertise of multiple DOE National User Facilities in one research proposal.  Successful applications will focus … proposals within the focused topic areas that can be completed on an accelerated timeline as compared with the … provides customized analysis, the JGI also participates in publication of results. …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in … use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … possess genomes and particle sizes that rival those of cellular organisms. Giant viruses challenge the traditional …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … tools to study this complexity, including single-cell and spatial transcriptomics barcode-based genetics …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … pathway, and I’ll have to do a whole show on it one of these days. If you listen to the Nancy Keller … way – the RiPP way, is to make a protein using the normal cellular way of making proteins, with a ribosome. Then, some …

… grow and have different perspectives– from the chemists on one side, microbiologists, and evolutionary biologists more … BARONA-GOMEZ: Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a … If we are only interested in that final product, which is completely potent and specific to the target we’re thinking …

… what genome mining is, if I want to explain that to someone who doesn’t know much about genetics or anything else, … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … of Earth’s Microbiomes. And what this is, is a data set of bacterial and archaeal genomes that were created – these are …

… The Joint Genome Institute and the Molecular Foundry have launched a … and expertise of both national user facilities in one research proposal.  Submit research proposals  here that … free of charge, including data such as fully annotated genome assemblies or differential gene expression results. …

… — and further advancing sequence applications, single cell genomics, biodesign, and metabolomics capabilities.    … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … The JGI provides users access to cutting-edge cell sorting, DNA amplification, and sequence analysis to …