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… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … uncultivated Bacteria and Archaea has steadily been widening since 2005. This gap is also reflected in the strongly … In particular during an era of ‘homology creep’, function prediction as purely based on annotation may not be …

…   Our Sequencing Technologies Group is well-integrated across JGI … the JGI’s focus on expanding molecular capabilities and functional genomics, scaling capacity through end-to-end … automation — and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics …

… Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and characterize genomic information … thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic … monitoring, bioremediation, and the discovery of novel enzymes and bioactive compounds. …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … We then investigate the coding potential to find novel functions that may impact microbiome structure and …

… recognized and credited for their work, while also adhering to the authorship policies of the journal in which the … that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts …

… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … soil ecosystems by combining metagenomics with other omics approaches, including especially metatranscriptomics, to …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast … and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic … in particular to study inter-organismal interactions. Novel approaches are being explored to predict microbial …

… The CSP Functional Genomics call is to enable users to perform state-of-the-art … genomics research and to help them translate genomic information into biological function.  The emphasis is on projects … the applicant.  Learn about the general review process or find details on the internal synthetic biology review process …

… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that … the quality of single-cell genomes and directly link functional information with individual cells. Research Team  … uniquely offers the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal …

… Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential … of “big data,” and artificial Intelligent/machine learning approaches in data analysis and interpretation is creating … of the functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their … work in the Metagenome Program uses several experimental approaches to assess microbial activity across ecosystems.  … By understanding how microbes contribute to ecosystem functions, the Program helps drive innovations that could …

… The Synthetic Biology lab is divided into a DNA synthesis production group and a synthetic … applications.  We are interested in:  characterizing novel enzymatic activities using phylogenomic driven approaches, and understanding the design principles for …