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… to identify and characterize genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … and reconstruct metabolic properties encoded within those genomes. Our aim is to more fully capture microbial and …

Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … and targeted gene searches to expand representation of uncultivated microbial lineages. Charting viral ‘dark … NMDC is a community-driven national effort aimed to develop standards, processes, and infrastructure for an integrated …

… involves both experimental and computational exploration of uncultivated viral diversity, characterization of molecular … and major challenges of host prediction methods for uncultivated phages.  Current Opinion in Virology .  49 , … Roux, S. et al. (2019) Minimum Information about an Uncultivated Virus Genome (MIUViG).  Nature Biotech .  37 …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … Metagenomics pipeline that utilizes internal analytical standards to accurately measure environmental microbiome … and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling strategies …

… to generate high-quality genomic datasets, particularly for uncultivated microorganisms, by sequencing large populations of bacteria … catalog : Beyond minimal draft and improved draft microbial genomes the program offers single-cell sequencing, …

… of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to … relationships and to provide valuable reference genomes in under-populated areas of the tree of life, as …

… tools and infrastructure as well as ensure cohesive data standards, the JGI partners with a number of facilities.  … … data on scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and understanding. JGI and …

… and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific … mass spectrometry Metabolite annotation based on chemical standards or computational approaches. Relative abundance of … mass spectrometry Metabolite annotation based on chemical standards or computational approaches. Relative abundance of …

… data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The Integrated Microbial Genomes group is focused on:  Developing state-of-the-art … Development and maintenance of the Integrated Microbial Genomes (IMG) data management system … As part of this …

I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … as seen on the phylogenetic tree, with new lineages of uncultivated genomes from the GEM catalog (in green) and … metabolomics, and natural products in plants, fungi, and microorganisms. If you want to collaborate, let us know. …

… and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … take the 100, 200 most important protein domains that are defining for biosynthetic pathways and let’s split these … kinds of data. And actually also for that we need also new standards and new platforms. So we’ve been recently working …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with … Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though not … has:  11 CSU educators working with the JGI 120 genomes claimed (or about one per student) Seven …