Search

… welcome back to Natural Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In … that you do, then it’s very easy to think that, OK, I find 25 gene clusters, there must be 25 new compounds. Or … that I was exchanging with people. So I think I wrote 3,000 emails in the course of one and a half year while …

… And you have these different types of particulate like 2.5, 10 PPMs and just the size of the particle and how far … there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re …

… out where I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … this is Challis et al, Chemistry and Biology, 2000, 211-224, 7:3 And so, you can then make predictions about … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… into DNA by active microbial populations (Hungate et al. 2015). With the development of high-throughput SIP (Nuccio et … microbiomes. mSystems0:e01744-24. https://doi.org/10.1128/msystems.01744-24 Oliver, T., Varghese, N., Roux, S. et … Sci Data 11 , 966 (2024). https://doi.org/10.1038/s41597-024-03826-8 Nayfach, S., Roux, S., Seshadri, R. et al. A …

… list available at Google Scholar. Dutkiewicz, Z. et al (2025) “ Proposal of Patescibacterium danicum gen. nov., sp. … phyl. nov .”  ISME Communications , Volume 5 Issue 1. Wittmers, F. et al (2024) “ Non-photosynthetic … meta-omic conclusions .”  Nature Communications Volume 15 Article 9873. Buscaglia, M. et all (2024) “ Adaptation …

… annotate, and bin viruses from metagenomes. mSystems 9:e00888-24. https://doi.org/10.1128/msystems.00888-24 Coclet, C., Sorensen, P.O., Karaoz, … RNA virome reveals diverse clades of bacteriophages. Cell 185, 21. https://doi.org/10.1016/j.cell.2022.08.023 Roux, S., …

… modules Currently 206 genomes have been selected with 11 published manuscripts published to-date Testimonials: … and publicly available datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes … care center in Finland. Microbiol Resour Announc 0:e00891-25. https://doi.org/10.1128/mra.00891-25 . B. Christenson, I. …

… because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … at several natural product enediyne structures, Ben’s 2015 paper on genome mining for enediynes is one of my …

… never forced it on me, but we always had these scientific news magazines lying around at home. And I would just pick … was bioengineering bio-process R&D, BBRD, a group of about 75 people. So our biggest project was the spinosyn family of … goals for secondary metabolism by downloading a copy of our 5-Year Strategic Plan, “Beyond Basepairs – A Vision for …

… APS, BioSANS typically has an acceptance rate of 12 to 15%, mainly due to resource limitations with our partner … Across the whole center our acceptance rate is close to 75%, but then depending on which capabilities are being …

… than HIV/AIDS does every year in the US and it has since 2005 even though we technically have a number of different … plants and bringing them back is not your jam, the good news is there’s this amazing resource that can be provided …