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… Dr. Baumgart joined the DOE Joint Genome Institute in 2018, following his doctoral research in synthetic biology and … in flowering plant gene regulation." Nature Plants 11, no. 8 (2025): 1514-1527. Lax, Carlos, Stephen J. Mondo, … biosensor." U.S. Patent 11,209,412, issued December 28, 2021. Baumgart, Leo, William Mather, and Jeff Hasty. …

… want to go back and listen to the first two parts ( part 1 is here and part 2 is here ) so you understand what’s … the number was. But I want to say it was like less than 10. Since, you know, a recent decade.  DAN: I’m sure that’s … to check her stat and she was absolutely correct. Since 2010 there have been eight new antibiotics added to the …

… welcome back to Natural Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In the … talk and that now I can bring it to you. So enjoy, episode 11 of Natural Prodcast. Alison Takemura: Marnix, where are …

… pairs. It was not linear, like Streptomyces , but circular. 10% of the genome encoded natural product pathways. Dan: … Brad: Yeah, at that time, that was new, right? Like, my god 10% of the genome makes small molecules that have, you know, … of changed over the years. And I think maybe over the last 10 years, I’ve really become a fan of having postdocs, and …

… And I set that up. And we finally got that to work 10 years later. But in the meantime there, we had people … a teaspoon of soil from outside, you maybe have to do a 10,000-fold dilution to plate that out. The deeper you go in the cave, the less dilution. You can be down to 1 on 100 in a deep portion of a cave. So it just– it really, …

… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … learn as much about it as possible starting with we picked 183 of them. And we sent that list to the Joint Genome … an unusual acyl-homoserine lactone signal . mBio. 2023 Aug 31;14(4):e0101023. doi: 10.1128/mbio.01010-23. Publication: …