Search

… resources empower students through isolation and genome sequencing of new fungal species.  Students collect fungi, … into iNaturalist. Myco-Ed has:  ~50 lineages selected for sequencing 16 genomes released 20 members from 15 … laboratories with minimal overhead (cost of media, ITS sequencing and tissue preparation), allowing participation …

… and the 90s. And so we started to be able to explore DNA sequencing and actually get to the DNA sequence – sequences … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less … We have a lot more data. Obviously, there’s been a lot of sequencing going on, especially at the JGI and in other …

… the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … whole spectrum from bulk soil being one of the most complex communities on earth, and the three-member community, and …

… An article summarizing the field of viral metagenomics, authored by JGI researchers Lee Call,  … Currently one of the best ways to study such viruses is by sequencing the bulk DNA or RNA contained in a sample that … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …

… Bill Fenical. And we connected to JGI through the Community Sequencing Program, and they worked with us to sequence two … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … at Monterey Bay, to be able to then do, at real time, sequencing on the underwater rover while it’s in the middle …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … about his move to microbiology, about drug discovery and why it’s so hard to succeed, and we talk about an ongoing … bring it into the lab. And I think that criterion explains why the natural products in the ocean weren’t studied up …

… it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … everything is funding, right, isn’t it? I thank JGI for sequencing a lot of fungi. But the thing with them – to get … sequence is really cheap. I’ve got colleagues that are sequencing dozens and dozens of fungi, mostly coming out of …

… influencing the microbes there,” said Simon Roux , the Viral Genomics Group Lead at the JGI.  To understand the … conditions and a specific microbial host to replicate. Sequencing genetic material directly from samples sidesteps … environmental metagenomes began to offer a window into viral existence. Along with highlighting the viruses in a …

… access to information regarding genome and metagenome sequencing projects, and their associated metadata, around … tools for analyzing the functional capability of microbial communities based on their metagenome sequence, in the … the largest publicly available collection of Uncultivated Viral Genomes, derived from genomes, metagenomes, and …

… lending their expertise in developing and managing public viral genomics resources such as analytical tools and data … workflows that allow researchers to easily analyze viral genomes. This includes (i) classifying viruses into … extensive track record of developing cutting-edge tools for viral genomics. Notable examples include CheckV , which …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … it was a big deal. And you really had– I mean, the whole sequencing endeavor, had a cost, how much blood, sweat, and …

… your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … JGI and this was before they were integrated. So I thought, why not feed it in there. And I went to group meeting and … community. For us, it’s these methane oxidizing bacterial communities that we like to look through as a lens, and …