Search

… biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … time called Genbiotics , which was a large program to find novel antibiotics. And this particular project focused … gene clusters. And I had heard the first rumors of people sequencing like these enormous numbers of genomes, like 20 …

… NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the wazoo out of anything that’s relevant to the … so it’s really functional genomics. And there’s a lot of sequencing based approaches, of course, now that we can use …

… DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … often use primary metabolites as building blocks to produce novel molecules. And so we’ve got glycosides being made into … is similar to primary metabolism. So if you were, you know, sequencing an organism for the first time, and you’ve never …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or … guess with along that line, with JGI, like how many are you sequencing currently? ALISON NARAYAN: Yeah. So– yeah, with …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic biology, … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … the JGI. And so now here at the JGI, I work with all of the sequencing data that the JGI produces to try to find and …

… For sequencing projects, once work is under way, raw sequence … More on Sequencing Projects …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … We find chemistry that’s known, or sometimes novel, but often known, and yet the clusters don’t look the … really exciting work on figuring out how to get genomic sequencing data for the fungus garden because it’s more …

… develops data science tools for workflow management and novel automations for DNA design, assembly and analysis …

… by generating data in three overarching categories: DNA Sequencing , DNA Synthesis and Metabolomics .  Many users …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … in order to put them together to build pathways, to make novel compounds, or to find analogs. And that was Warp …

… environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the … The Fungal & Algal Program harnesses cutting-edge sequencing technologies and advanced genomic analysis to … and biogeochemistry. The program’s focus is on large-scale sequencing efforts that survey the vast phylogenetic and …

… Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … facility, evolved, and as we started to do more than just sequencing, we thought the name community sequencing program … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …