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… really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA … And you would scan those pieces by hybridization or maybe sequencing if you were rich enough. [CHUCKLES] And once you … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… they then ship samples—such as DNA and RNA for sequencing—to JGI. Users are responsible for covering the … to work with single organisms and mixed cultures of fungi, algae, protists, bacteria, archaea, viruses, plants, … proposal include snRNAseq and snATACseq library prep and sequencing? …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore … The Microbial Program focuses on using advanced sequencing technologies to explore microbial diversity — … datasets, particularly for uncultivated microorganisms, by sequencing large populations of bacteria and archaea in …

… were able to identify specific genes that allow the algae to adapt to sudden drops in salt levels, enabling it … more fresh water — and less salt — near the surface where algae grow. Armed with a better understanding of the alga’s … This was facilitated in part by RNA library preparation and sequencing from the U.S. Department of Energy (DOE) Joint …

… summary above^ as well ] The Science The recipe for growing algae as a source of sustainable biofuels seems fairly simple: place these algae in a container with access to sunlight, water and … Summary On the list of candidate bioenergy feedstocks, algae are tiny but mighty. An analysis in the 2017 …

… NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the wazoo out of anything that’s relevant to the … core science programs which are microbes, and fungi, and algae plants, synthetic biology. And so we have, I think, …

… scientists sequenced the genomes of four  Zygnematophyceae algae, which were isolated from diverse freshwater … Arising in tandem from the same ancestor, these algae are considered sisters to land plants, based on shared … critical insights into the common ancestry of these algae and land plants. Researchers identified key genes …

… UC Berkeley plant biologist Sabeeha Merchant explains why she works on this alga, how researchers managed to …

… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … because – mainly it’s due to the emerging technology on DNA sequencing and synthetic biology. But also the metagenomics … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic biology, … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … the JGI. And so now here at the JGI, I work with all of the sequencing data that the JGI produces to try to find and …

… foundation for metabolic engineering in oleaginous algae. By creating a telomere-to-telomere nuclear genome … genetic modifications usually insert randomly in other algae, this organism lets scientists place new genes … understand how genes with unusual structures work in green algae. The genome is remarkably simple with only 7,500 …

… For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … with DOE mission-relevant projects that call for expansive sequencing, synthetic biology, and metabolomics capabilities … Letters of Intent. Proposals may include synthetic biology, sequencing, and metabolomics. Proposals may include …