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… find, things that are of interest. And usually, in terms of bacteria and secondary metabolism, those things that we want … really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which … reservoir of secondary metabolites produced by bacteria, fungi, algae and plants. These compounds are key … We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma …

… of microbial metabolism towards a minority of cultivated bacteria, still persists to date. Research Team    … show that the gap between cultivated and uncultivated Bacteria and Archaea has steadily been widening since 2005. … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary …

… before– or kind of around about when the first genome sequencing was done. But natural products– marine natural … biology classes in undergrad, but my PhD was an actinobacteria. And I tell all my students this now, but when I … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to …

… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the 40,000 from bacteria, there’s …

… created in 1997 to unite the expertise and resources in DNA sequencing, informatics, and technology development … accomplishment, the JGI went on to advance basic science by sequencing scores of microbial species as well as several …

… any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by … for Federal Agencies , DNA Synthesis Appendix  and DNA Sequencing Appendix are available for download.)  After your …

… through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … is similar to primary metabolism. So if you were, you know, sequencing an organism for the first time, and you’ve never …

… been dominated for … well, as long as I can remember, by bacterial research.  So it was great to hear her passion and … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … everything is funding, right, isn’t it? I thank JGI for sequencing a lot of fungi. But the thing with them – to get …

… Industry Partners access to our vast set of resources:  JGI sequencing technologies include scaling technologies and … JGI users get access to cutting-edge capabilities including sequencing, synthesis and metabolomics. Many users rely on a …

… about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … technology.] BETSY PARKINSON: OK. DNA affinity purification sequencing. And so the way this essentially works is you …

… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours …     Q4 2026 175     2,208     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on … even though an individual may have several projects/roles. Sequencing Quarter Total Bases (Trillions) Operating Hours …