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… welcome back to Natural Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In … to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on … that I was exchanging with people. So I think I wrote 3,000 emails in the course of one and a half year while …

… there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and … Metabolites Collaboratory SMC Workshop Materials from the 2023 JGI Annual Meeting Using the SMC Website API Endpoints …

… where I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … found in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you … this is Challis et al, Chemistry and Biology, 2000, 211-224, 7:3 And so, you can then make predictions about …

… into DNA by active microbial populations (Hungate et al. 2015). With the development of high-throughput SIP (Nuccio et al. 2022) and terabase-scale metagenome combined assemblies … microbiomes. mSystems0:e01744-24. https://doi.org/10.1128/msystems.01744-24 Oliver, T., Varghese, N., Roux, S. et …

… list available at Google Scholar. Dutkiewicz, Z. et al (2025) “ Proposal of Patescibacterium danicum gen. nov., sp. … ISME Communications , Volume 5 Issue 1. Wittmers, F. et al (2024) “ Non-photosynthetic lineages sibling to Cyanobacteria …

… Coclet C, Camargo AP, Roux S. (2024) MVP: a modular viromics pipeline to identify, filter, … annotate, and bin viruses from metagenomes. mSystems 9:e00888-24. https://doi.org/10.1128/msystems.00888-24 Coclet, C., Sorensen, P.O., Karaoz, …

… recruit new talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in … development and adoption of classroom modules Currently 206 genomes have been selected with 11 published manuscripts published to-date Testimonials: …

… right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … look at several natural product enediyne structures, Ben’s 2015 paper on genome mining for enediynes is one of my …

… never forced it on me, but we always had these scientific news magazines lying around at home. And I would just pick … screening platform where we’d look at 10,000, 15,000, 20,000 mutants a week. We started doing a whole bunch of … Metabolites Science Program . Since his arrival in 2017, Nigel has led a vision for the JGI that sees secondary …

… materials. The proposal submission deadline is March 31, 2026 .  … (CMMs). Click for a list of CMMs and the results of the 2023 DOE Critical Materials Assessment . While we expect most … the Molecular Foundry, the project needs to be scoped for 12 months or less. We can help you scope that part of the …

… then my lab pleaded mercy, and I said, OK, we’ll just do 2011 to present day. And it was still like 4,000 articles we … plants and bringing them back is not your jam, the good news is there’s this amazing resource that can be provided … you can place a pre-order for the paperback (available June 2022). You might also enjoy Foodie Pharmacology – a science …