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    Data yielded from RIViT-seq increased the number of sigma factor-gene pairs confirmed in Streptomyces coelicolor from 209 to 399. Here, grey arrows denote previously known regulation and red arrows are regulation identified by RIViT-seq; orange nodes mark sigma factors while gray nodes mark other genes. (Otani, H., Mouncey, N.J. Nat Commun 13, 3502 (2022). https://doi.org/10.1038/s41467-022-31191-w)
    Streamlining Regulon Identification in Bacteria
    Regulons are a group of genes that can be turned on or off by the same regulatory protein. RIViT-seq technology could speed up associating transcription factors with their target genes.

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    (PXFuel)
    Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
    In a special issue of the journal Synthetic Biology, JGI scientific users share how they’ve worked with the JGI DNA Synthesis Science Program and what they’ve discovered through their collaborations.

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    A genetic element that generates targeted mutations, called diversity-generating retroelements (DGRs), are found in viruses, as well as bacteria and archaea. Most DGRs found in viruses appear to be in their tail fibers. These tail fibers – signified in the cartoon by the blue virus’ downward pointing ‘arms’— allow the virus to attach to one cell type (red), but not the other (purple). DGRs mutate these ‘arms,’ giving the virus opportunities to switch to different prey, like the purple cell. (Courtesy of Blair Paul)
    A Natural Mechanism Can Turbocharge Viral Evolution
    A team has discovered that diversity generating retroelements (DGRs) are not only widespread, but also surprisingly active. In viruses, DGRs appear to generate diversity quickly, allowing these viruses to target new microbial prey.

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    Photograph of a stream of diatoms beneath Arctic sea ice.
    Polar Phytoplankton Need Zinc to Cope with the Cold
    As part of a long-term collaboration with the JGI Algal Program, researchers studying function and activity of phytoplankton genes in polar waters have found that these algae rely on dissolved zinc to photosynthesize.

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    This data image shows the monthly average sea surface temperature for May 2015. Between 2013 and 2016, a large mass of unusually warm ocean water--nicknamed the blob--dominated the North Pacific, indicated here by red, pink, and yellow colors signifying temperatures as much as three degrees Celsius (five degrees Fahrenheit) higher than average. Data are from the NASA Multi-scale Ultra-high Resolution Sea Surface Temperature (MUR SST) Analysis product. (Courtesy NASA Physical Oceanography Distributed Active Archive Center)
    When “The Blob” Made It Hotter Under the Water
    Researchers tracked the impact of a large-scale heatwave event in the ocean known as “The Blob” as part of an approved proposal through the Community Science Program.

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    A plantation of poplar trees. (David Gilbert)
    Genome Insider podcast: THE Bioenergy Tree
    The US Department of Energy’s favorite tree is poplar. In this episode, hear from ORNL scientists who have uncovered remarkable genetic secrets that bring us closer to making poplar an economical and sustainable source of energy and materials.

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    HPCwire Editor's Choice Award (logo crop) for Best Use of HPC in the Life Sciences
    JGI Part of Berkeley Lab Team Awarded Best Use of HPC in Life Sciences
    The HPCwire Editors Choice Award for Best Use of HPC in Life Sciences went to the Berkeley Lab team comprised of JGI and ExaBiome Project team, supported by the DOE Exascale Computing Project for MetaHipMer, an end-to-end genome assembler that supports “an unprecedented assembly of environmental microbiomes.”

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    With a common set of "baseline metadata," JGI users can more easily access public data sets. (Steve Wilson)
    A User-Centered Approach to Accessing JGI Data
    Reflecting a structural shift in data access, the JGI Data Portal offers a way for users to more easily access public data sets through a common set of metadata.

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    Phytozome portal collage
    A More Intuitive Phytozome Interface
    Phytozome v13 now hosts upwards of 250 plant genomes and provides users with the genome browsers, gene pages, search, BLAST and BioMart data warehouse interfaces they have come to rely on, with a more intuitive interface.

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    screencap from Amundson and Wilkins subsurface microbiome video
    Digging into Microbial Ecosystems Deep Underground
    JGI users and microbiome researchers at Colorado State University have many questions about the microbial communities deep underground, including the role viral infection may play in other natural ecosystems.

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    Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical output due to growth and viability constraints. Cell extracts provide an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By separating the production of enzymes (during growth) and the biochemical production process (in cell-free reactions), this framework enables biosynthesis of diverse chemical products at volumetric productivities greater than the source strains. (Blake Rasor)
    Boosting Small Molecule Production in Super “Soup”
    Researchers supported through the Emerging Technologies Opportunity Program describe a two-pronged approach that starts with engineered yeast cells but then moves out of the cell structure into a cell-free system.

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    These bright green spots are fluorescently labelled bacteria from soil collected from the surface of plant roots. For reference, the scale bar at bottom right is 10 micrometers long. (Rhona Stuart)
    A Powerful Technique to Study Microbes, Now Easier
    In JGI's Genome Insider podcast: LLNL biologist Jennifer Pett-Ridge collaborated with JGI scientists through the Emerging Technologies Opportunity Program to semi-automate experiments that measure microbial activity in soil.

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    A view of the mangroves from which the giant bacteria were sampled in Guadeloupe. (Hugo Bret)
    Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
    Harnessing JGI and Berkeley Lab resources, researchers characterized a giant - 5,000 times bigger than most bacteria - filamentous bacterium discovered in the Caribbean mangroves.

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    In their approved proposal, Frederick Colwell of Oregon State University and colleagues are interested in the microbial communities that live on Alaska’s glacially dominated Copper River Delta. They’re looking at how the microbes in these high latitude wetlands, such as the Copper River Delta wetland pond shown here, cycle carbon. (Courtesy of Rick Colwell)
    Monitoring Inter-Organism Interactions Within Ecosystems
    Many of the proposals approved through JGI's annual Community Science Program call focus on harnessing genomics to developing sustainable resources for biofuels and bioproducts.

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    Coloring the water, the algae Phaeocystis blooms off the side of the sampling vessel, Polarstern, in the temperate region of the North Atlantic. (Katrin Schmidt)
    Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
    As warm-adapted microbes edge polewards, they’d oust resident tiny algae. It's a trend that threatens to destabilize the delicate marine food web and change the oceans as we know them.

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News & Publications
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February 9, 2015

Exploring Uncultivable Microbes at AAAS

Susannah TringeSESSION TITLE: Novel Technologies for Exploring the Uncultivated Microbial Majority WHEN: 1:00pm on Friday, February 13, 2015 WHERE: Room LL20C (San Jose Convention Center) Susannah Tringe and Tanja Woyke, the respective heads of our Metagenome and Microbial Programs, have organized a session at this year’s American Association for the Advancement of Science (AAAS) Meeting, which… [Read More]

January 7, 2015

CAMI Hosts Community Challenge for Assessing Metagenomes

Logo of CAMI (Critical Assessment of Metagenome Interpretation)  Current CAMI Schedule for Participants: March 27, 2015 “Challenge Part I” opens: Read data sets posted for assembly and read based profiling/binning May 8, 2015 Deadline for “Challenge Part I,” Assemblies May 9, 2015 “Challenge Part II” opens: Gold standard assemblies posted for contig-based profiling/binning May 27-29, 2015 1st CAMI Evaluation Meeting. Details: http://cami-challenge.org/evaluation_meeting June 19, 2015 Deadline… [Read More]

January 5, 2015

2014 Food Drive Collection Tops 1,700 lbs

Contra Costa Food Bank barrels picked up at the JGI on the last day of the 2014 Holiday Food DriveThe annual JGI Holiday Food Drive of 2014 brought nearly a ton of food to the the Food Bank of Contra Costa and Solano. Over half of the total came from the family of software developer Bobby Otillar, who pledged to match the amount of food donated by fellow JGIers pound-for-pound for the third year in a row. This… [Read More]

November 20, 2014

NCBI Genomes Reprocessed using IMG’s Annotation Pipelines and Distributed via JGI’s Genome Portals

The Integrated Microbial Genomes (IMG) system provides tools for analyzing the structural and functional annotations of metagenomes and single genomes in a comparative context. At the core of the IMG system is a data warehouse that contains genome and metagenome datasets (sets of genome sequence fragments from microbial communities) sequenced at the DOE Joint Genome… [Read More]

November 11, 2014

Shipworm project in the Washington Post

“Shipworms were already weird animals, but they just got weirder. The ocean-dwelling clams, which actually look much more like slimy worms, are some of the only creatures in the world that can eat wood. Now scientists have figured out that shipworms are even more unique than we thought…” The Washington Post article was published November 11, 2014. Learn… [Read More]

October 22, 2014

Celebrating National Bioenergy Day

Boardman OR poplar plantationIn honor of National Bioenergy Day, we thought we’d highlight some of our recent projects that are related to developing plant biomass, as well as agricultural waste and forestry byproducts, to generate heat and energy. Among the plants being considered for biomass crops are eucalyptus trees, which grow in 100 countries and cover over 40… [Read More]

September 26, 2014

Training the Next Generation of Talent

mentors and interns for JGI-UC Merced internship programNew Graduate Internship Program Builds Bridges Between DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user facility, Keedrian Olmstead was back on campus at the University of California, Merced to start orientation as a… [Read More]

September 19, 2014

nucleotid.es genome assembly tool in GenomeWeb

“Nucleotid.es, a publicly available repository developed by a researcher at the Joint Genome Institute, aims to provide a comprehensive list of genome assemblers and associated benchmarks that will help researchers in the genomics community select and use the most appropriate assembly tools for their sequencing projects.” Full story on GenomeWeb. (Note: Free registration may be… [Read More]

July 17, 2014

In Memoriam: Falk Warnecke

Falk WarneckeFalk Warnecke was a postdoctoral fellow at the DOE JGI’s Microbial Ecology Program from March 2005 until June 2009. Among the publications that resulted from his work here, he was first author on the termite hindgut metagenome paper that appeared in Nature. Warnecke died on July 15, 2014 at the age of 42. Within a… [Read More]

May 5, 2014

#JGInPoetry – Genomics in Verse

JGI UM9 shirtOur call for verses to help us communicate our science yielded several poems, a couple of which even met the writing challenges we set. We’ve shared these on social media and we hope the muse continues to inspire as we look forward to receiving more poems about genomics, energy and environment.  “Ode to a Gutless… [Read More]
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