- BS in Chemistry, Moscow Institute of Fine Chemical Technology, Russia;
- PhD in Physical Chemistry, Russian Academy of Sciences, Moscow
Dr. Dubchak’s Ph.D. in Physical Chemistry had specific emphasis on Crystallography and Computational Methods. In the 1990’s, during her postdoctoral training at the University of California in Berkeley, she realized the potential of the emerging study of genomic data and switched to the fields of computational biology and bioinformatics. Since then, she has authored more than 100 academic articles and led a group that focuses on the analysis, organization, and visualization of large volumes of genomics information. Her team has developed a number of excellent visualization tools, including the VISTA family of programs for comparative genomics, which has become one of the major systems used by the biological community. The international popularity of the tools developed by Dr. Dubchak’s lab can be attributed to innovative features, exceptionally user-friendly and modern interfaces, and meticulous attention to biological details.
Major Databases and Software
- VISTA – a comprehensive suite of programs and databases for comparative analysis of genomic sequences.
- VISTA Region Viewer (RViewer) is an interactive on-line tool for comparing and prioritizing genomic intervals.
- VISTA Enhancer Browser – a central resource for experimentally validated human and mouse noncoding fragments with gene enhancer activity
- RegTransBase – a database of regulatory interactions based on literature and an expertly curated database of transcription factor binding sites.
- RegPrecise – collection of manually curated inferences of regulons in prokaryotic genomes
- RegPredict – an integrated system for regulon inference in prokaryotes by comparative genomics approach.
- Elviz – interactive visualization tool for exploration of metagenome assemblies